Antifungal shampoo for dogs being used during a bath to help treat yeast and fungal skin infections

Antifungal Shampoo for Dogs (2026): Best Medicated & Natural Options in the UK

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By Syed

When dogs develop persistent itching, greasy patches, flaking skin, or a strong musty odour, a standard grooming shampoo is often not enough. In these cases, an antifungal shampoo for dogs can help support skin hygiene by targeting yeast and fungal overgrowth while cleansing the coat effectively.

This guide is written for UK dog owners looking for targeted antifungal shampoo options, not general-purpose grooming products. It focuses on shampoos commonly used to manage yeast-related skin issues, fungal dermatitis, and recurring greasy or smelly coats.

How to Choose the Right Antifungal Shampoo for Your Dog

Not all skin problems are fungal, which is why choosing the right type of shampoo matters.

An antifungal shampoo is typically considered when dogs show signs such as:

  • A strong yeasty or musty smell
  • Greasy or oily patches on the coat
  • Flaking, scaling, or thickened skin
  • Recurring irritation that doesn’t improve with mild shampoos

These shampoos often contain medicated or antimicrobial ingredients designed to cleanse the skin thoroughly and help reduce microbial build-up. They are different from everyday or oatmeal-based shampoos, which mainly soothe dryness or irritation.

💡 Pro Tip: The 10-Minute Rule
Medicated dog shampoos are not like regular grooming washes. Most antifungal formulas need 5–10 minutes of contact time on the skin to work properly. Rinsing too quickly can reduce their effectiveness.

If your dog’s symptoms are limited to mild itching without odour or greasiness, a gentler option may be more appropriate. In those cases, you may want to explore alternatives, such as a shampoo formulated for itchy skin, rather than jumping straight to antifungal formulas. Many fungal flare-ups are actually triggered by using the wrong products. If you’re unsure, here’s why you shouldn’t use human shampoo on dogs and how it can disrupt their skin barrier.

This article focuses on topical support through shampoo use only. Persistent or severe skin issues should always be discussed with a qualified veterinarian.

Best Antifungal Shampoos for Dogs: Full Reviews

Below are five carefully selected antifungal and antimicrobial shampoo options, categorised by use case. This structure allows you to choose a product based on the severity of symptoms, formulation type, and personal preference, rather than guessing.

Best Overall Antifungal Shampoo for Dogs

1. DOUXO S3 PYO Shampoo | Antibacterial & Anti-Yeast

  • Antibacterial & Antifungal Action: Contains 3% chlorhexidine digluconate with Ophytrium to help cleanse and manage bacterial and yeast imbalance on skin and coat.
  • Hydrating Formula: Helps maintain the skin’s natural moisture while cleansing, leaving the coat soft and conditioned.
  • Vet Recommended: Part of a veterinary dermatology range commonly suggested for pets with microbial or irritated skin.
  • Hypoallergenic Fragrance: Mild coco-vanilla scent suitable for sensitive dogs and frequent use.
  • Free From Harsh Additives: Formulated without soaps, sulfates, parabens, colourants or phthalates for better skin tolerance.

Star Rating: ★★★★☆ (4.7/5)

Why it’s a top pick

Douxo S3 Pyo is one of the most vet-trusted antifungal shampoos in the UK, formulated specifically for pets prone to yeast infections, bacterial skin conditions, or allergy-triggered itching. Its use of chlorhexidine and Ophytrium makes it a powerhouse for balancing the skin microbiome while being gentle enough for repeated use. It’s a prescription-grade formula that works fast, yet is soothing and non-irritating — even for pets with sensitive skin.

Specifications

  • Bottle Size: 200ml
  • Scent: Light vanilla-coconut (fragrance-free option)
  • Made in: France (vet-distributed across UK)
  • Best for: Dogs and cats with fungal, bacterial, or mixed skin infections
  • Additional Info: Dermatologist-recommended for Malassezia dermatitis

✅ Reasons to Buy

  • Clinically proven to reduce yeast and bacterial skin infections
  • Non-drying and safe for repeated use on sensitive skin
  • High-performance formula backed by UK vets
  • Doesn’t sting or irritate wounds or broken skin
  • Trusted across vet surgeries and specialist pet retailers

🗨️ Customer Feedback

“Cleared up my Frenchie’s skin within a week!” — Dog owner

“Recommended by my vet for chronic yeast and it’s the only one that worked.” — Verified purchaser

❌ Reasons to Avoid

  • A prescription may be required in some cases
  • Higher price point than general-purpose shampoos
  • Not scented — may not appeal to owners wanting a stronger fragrance

📝 Mini Verdict

If your dog suffers from persistent itching, hot spots, or yeast-based skin issues, Douxo S3 Pyo is a top-shelf solution that delivers clinical results. While it’s pricier and less “fragranced” than cosmetic shampoos, its therapeutic effect and vet backing make it worth every drop. One of the strongest antifungal shampoos available without compromise.

Best Medicated Antifungal Shampoo (Vet-Trusted Option)

2. VetPlus Coatex Medicated Dog Shampoo (500 ml)


  • Antibacterial & Antifungal Action: Contains a blend of chloroxylenol, salicylic acid and sodium thiosulfate to help cleanse the skin and support control of bacteria and fungi on the coat.
  • Deep Cleansing Formula: Designed to remove odour, scales, crusts and dandruff for dogs with greasy or flaky skin.
  • Neutral pH & Gentle: pH-neutral, soap-free formulation that’s gentle on skin while still effective for regular use when needed.
  • Odour Control: Specifically formulated to help deodorise coats prone to musty or unpleasant smells due to microbial imbalance.
  • Routine Support: Lathers well and rinses clean, making it practical as part of a regular antifungal grooming routine.

Star Rating: ★★★★☆ (4.8/5)

Why it’s a top pick

VetPlus Coatex Medicated Shampoo is specially formulated to provide antibacterial and antifungal cleansing for dogs with flaky, greasy, or odorous skin. Its neutral pH and gentle lather make it suitable for dermatological support without stripping essential oils, helping remove dandruff, scales, and crusts while improving overall coat condition. It’s often recommended alongside a targeted skin care routine for dogs showing signs of microbial imbalance. Because it deeply cleanses the coat and skin, it may also help wash away surface debris associated with external parasites such as fleas and ticks, making it a useful option within a broader skin-care and hygiene routine.

Specifications

  • Volume: 500 ml
  • Scent: Mild / Unscented
  • Key Features: Antibacterial, antifungal, deep cleansing, deodorising
  • Suitable For: Dogs with greasy, flaky, or smelly skin
  • Formulation: pH neutral and gentle yet effective 

Reasons to Buy

  • Antibacterial and antifungal formulation helps cleanse and reduce skin issues
  • pH-neutral, gentle yet effective deep cleansing action
  • Helps remove dandruff, odour and skin debris
  • Suitable for dogs with recurring greasy or flaky coats

Reasons to Avoid

  • Specialist use only — overkill for mild dry skin
  • Potentially less suitable for dogs with purely cosmetic grooming needs

💬 Customer Feedback

  • “Worked wonders. My golden retriever’s red hot spots went from painful to healed after gentle use with two washes.” — Verified purchaser
  • “Has a lovely fresh smell, lathers well and leaves my dog’s coat soft and shiny.” — Feefo reviewer

📝 Mini Verdict

VetPlus Coatex Medicated Shampoo is a strong medicated-style antifungal shampoo for dogs with suspected yeast or fungal-related skin issues. Its antibacterial and antifungal properties, combined with deep cleansing action and neutral pH, make it ideal for pets with persistent greasy skin and odour. Great as a supportive option within an antifungal grooming routine, especially when combined with other targeted care steps. 

Best Antifungal Shampoo for Yeast & Greasy Skin

3. ICF Zincoseb Dog Shampoo (250 ml)

  • Veterinary‑Formulated Antifungal & Antibacterial: Contains salicylic acid, colloidal sulphur, chlorhexidine digluconate and zinc gluconate for deep skin cleansing and fragrance‑neutralising action without harsh stripping.
  • Keratolytic & Odour‑Controlling: Salicylic acid exfoliates scaly skin and unclogs pores, while zinc gluconate helps rebalance oily or flaky skin and reduce malodour.
  • Soothes & Moisturises: Enriched with lanolin, lactic acid and betaine to hydrate and soften itchy, irritated coat and skin.
  • Clinically Proven Dermatitis Support: Studied in dogs with seborrhoeic dermatitis—100 % tolerability at 2 weeks and 80 % owner satisfaction at 4 weeks.
  • Puppy Safe & Usage : Apply 0.5 ml/kg to damp coat, leave for 5–6 minutes before rinsing; use 1–2 times weekly for at least 3–4 weeks.

Star Rating: ⭐⭐⭐⭐⭐ (4.5/5)


Why it’s a top pick

ICF Zincoseb is a trusted veterinary-grade shampoo frequently recommended in UK clinics for managing dry, itchy, flaky or oily skin conditions. Its combination of antifungal, antibacterial, and keratolytic ingredients makes it ideal for treating yeast dermatitis, seborrhoea, and skin odour issues. Rich in moisturising agents and effective cleansing compounds, it’s robust enough for therapeutic use yet gentle enough for puppy skin.

Specifications

  • Bottle Size: 250 ml
  • Scent: Light scent to mask odours from skin flaking 
  • Made in: Typically Italy or EU, distributed in UK veterinary supply chains
  • Best for: Dogs (and cats) with flaky, oily, itchy or odorous skin; Seborrhoeic dermatitis; Malassezia overgrowth
  • Additional Info: Safe for puppies (3 months+), use 1–3 times weekly for 3–4 weeks or as directed by a vet. Leave shampoo on for 5–6 minutes before rinsing

✅ Reasons to Buy

  • Proven antifungal, antibacterial and exfoliating action for persistent skin conditions
  • Hydrating formula—lanolin and lactic acid soothe and restore moisture balance
  • Excellent vet and customer ratings in UK pet‑care networks
  • Suitable for puppies, safe with regular use under vet supervision
  • Effective at controlling odour, oil buildup and visible flaking

🗨️ Customer Feedback

“This shampoo works!! My little dog’s skin condition is now well under control. I use Zincoseb once a week… no more itching & …” — Amazon UK feedback 

“A great product at a great price … Highly recommended … Super smooth—it’s the best” — UK buyer review on eBay 

❌ Reasons to Avoid

  • Requires a prescription or a veterinary supply in some regions
  • A stronger medicated approach may be unnecessary for mild or cosmetic-only skin issues
  • It may feel harsh to use too frequently on dry skin without a follow-up moisturiser

📝 Mini Verdict

ICF Zincoseb is an excellent choice for dogs experiencing dermatological issues such as dandruff, yeast overgrowth, and oily or flaky skin. Prescribed by vets, backed by positive reviews, and designed to cleanse and restore deeply, it outperforms general grooming shampoos in therapeutic efficiency—ideal where effective antifungal and antibacterial care is needed.

Best Broad-Spectrum Antimicrobial Shampoo

4. Aqueos Antibacterial, Antiviral & Antifungal Dog Shampoo (200 ml / 1L / 5L)

  • Lab-Tested Antimicrobial Protection: Proven to kill viruses, bacteria and fungi according to UK EN standards—effective yet gentle on skin.
  • Versatile & Deodorising: Ideal for dogs that roll in mud or badger/fox smells—neutralises odour instead of masking it.
  • Gentle & Biodegradable: Fragrance-free, alcohol- and bleach-free, pH neutral, <1% chemical content; suitable for all ages including puppies.
  • Great Value Sizes: Available in 200 ml, 1 L, and 5 L formats; dilutable up to 20:1 for budget-friendly use.

Star Rating: ⭐⭐⭐⭐☆ (4.4/5)


Why it’s a top pick

Aqueos offers an impressive, lab-tested antimicrobial shampoo that bridges the gap between everyday care and veterinary-level hygiene. Its unique combination of virucidal, bactericidal and fungicidal action—while remaining extremely mild—makes it suitable for dogs with itchy skin, rolled-in muck, or general skin discomfort. Because it’s UK-manufactured, vegan-friendly, biodegradable, and endorsed by professional groomers, it serves as a reputable, no‑prescription alternative for routine cleansing or pre- and post‑grooming care.

Specifications

  • Bottle Sizes Available: 200 ml, 1 L, 5 L
  • Scent: Fragrance-free / very mild fresh scent
  • Made in: United Kingdom
  • Best for: All coat types, smelly or itchy dogs, minor skin irritations, muddy or odorous coats
  • Additional Info: Dilutable up to 20:1; safe for puppies; professional household and kennel use; biodegradable packaging 

✅ Reasons to Buy

  • Independently validated antimicrobial (virus, bacteria, fungi tested) efficacy
  • Gentle enough for all ages and lots of use; suitable post-muddy walks
  • Effective deodoriser—removes strong odours, not just covers them
  • Great value—especially in litres or bulk sizes
  • UK-based, cruelty-free, vegan, pH neutral, biodegradable formula

🗨️ Customer Feedback

“Excellent shampoo, soothes itching, leaves the coat beautifully clean and shiny, and only a delicate scent.” — Verified purchaser on VioVet  

“Does what it says it does! Used on a teacup yorkie with skin problems… coat was soft and gleaming and skin settled within the hour.” — Amazon/eBay reviewer feedback

❌ Reasons to Avoid

  • Not prescription-strength—won’t treat ringworm, mites, Demodex or serious infections (vets may recommend medicated shampoos instead) 
  • Lacks moisturising or hydrating agents—less suited for very dry or flaky skin
  • Low or no lather may feel unfamiliar to some users
  • Fragrance‑free may not appeal to owners wanting a stronger scent

📝 Mini Verdict

Aqueos stands out as a highly ethical, lab-certified antimicrobial shampoo that delivers both cleanliness and deodorisation in one mild, no-fuss formula. Extremely well-priced and safe for frequent use, it’s a standout choice for dogs that roll in muck, suffer mild itch or odour issues—or need a hygienic wash after hikes. Not a replacement for vet-prescribed antifungals, but excellent as a supportive, everyday antimicrobial shampoo.

Best Natural Antifungal Alternative (Non-Chemical Option)

5. Cooper & Gracie Dog Shampoo for Itchy Skin (500 ml)

  • 100% Natural & Cruelty‑Free Formula: Made in the UK using organic essential oils like peppermint, spearmint, tea tree and clove—free from chemicals or preservatives and safe for frequent use.
  • Antibacterial & Antifungal Action: Designed to soothe itchy, irritated skin and support healing of minor grazes using naturally-derived antiseptics from essential oils.
  • Puppy‑Safe & Gentle: Low-lather, fast-absorbing and hypoallergenic—ideal for puppies and dogs with sensitive skin.
  • Trustworthy UK Brand: Offers a 90‑day money-back guarantee and responsive UK-based customer support.

Star Rating: ⭐⭐⭐⭐⭐ (4.5/5)


Why it’s a top pick

Cooper & Gracie’s shampoo is a natural, UK-formulated solution ideal for dogs with sensitive or itchy skin. With essential oils like tea tree, peppermint, spearmint and clove, it soothes inflammation, hydrates the skin and offers mild antimicrobial action—without any harsh chemicals. While it’s not veterinary-grade, many dog owners report relief from scratching and improved coat condition after just a few washes. Their 90‑day guarantee and responsive UK customer service further underscore their trustworthiness.

Specifications

  • Bottle Size: 500 ml
  • Scent: Herbal-clove blend with peppermint and spearmint notes
  • Made in: United Kingdom
  • Best for: Dogs with dry, itchy or sensitive skin; minor skin irritations or inflammation
  • Additional Info: Vegan, essential-oil based, low-foam, cruelty-free, money-back guarantee

✅ Reasons to Buy

  • Soothes itching and calms irritated skin naturally
  • Moisturises and softens coat using natural oils
  • Hypoallergenic (chemical-free) formula suitable for puppies
  • Easy to rinse with minimal sudsing
  • Backed by a 90-day satisfaction guarantee and UK support

🗨️ Customer Feedback

“This shampoo has been an absolute lifesaver for my dog… alleviated yeast symptoms and sensitive skin issues.” — Trustpilot user 

“The smell is herbal and really pleasant… it DOES both soothe and lessen the desire to scratch.” — Amazon reviewer

❌ Reasons to Avoid

  • Lacks clinical trials or vet endorsement (not a prescription product)
  • Some users feel the scent too mild or inexpensive for long-term use
  • Spray or bottle sometimes lacks a trigger nozzle, making application fiddly 

📝 Mini Verdict

An affordable, natural shampoo for reducing itchiness and soothing sensitive skin. While it’s not a prescription-strength antifungal, many dog owners praise its calming herbal formula and moisture benefits. Ideal for milder skin conditions or as part of a grooming routine for sensitive pups.


How Do I Know if My Dog Needs Antifungal Shampoo?

Pet owners often wonder about the signs or symptoms that indicate their dog may need an antifungal shampoo. Common indicators include persistent itching, which may lead to excessive scratching or biting at the skin. If you notice these signs, an antifungal shampoo can help alleviate discomfort and manage the fungal infections affecting your dog’s skin.

Redness, irritation, flaky or scaly patches, and unusual odours emanating from the coat can signal a fungal infection. Additionally, hotspots or bald patches may develop due to ongoing irritation. 

If you notice any of these symptoms, it’s advisable to consult your veterinarian for proper diagnosis and treatment. They will then be able to advise on the best medicated dog shampoos.

For dogs with mild itching that isn’t linked to fungal overgrowth, a gentler option may be more suitable. See our guide to the best shampoo for dogs with itchy skin.


Buying Guide for Antibacterial and Antifungal Shampoo for Dogs
Infographic buying guide for the best antifungal shampoo for dogs. Step 1: Read the label for soothing ingredients like Aloe Vera and Oatmeal. Step 2: Check for dog-safe pH balance (7.0-7.5) vs human skin (5.5). Step 3: Let the medicated shampoo sit for 10 minutes before rinsing.
Quick Guide: Always check the ingredients, ensure the pH is balanced for dogs (not humans!), and follow the 10-minute rule for antifungal effectiveness.

When selecting the right antifungal shampoo for dogs, consider several key factors to ensure you choose a product that meets your pet’s specific needs. Choosing the wrong product can lead to ineffective treatment or worsen your dog’s skin condition.

Quick Buying Guide: What to Look For

Brand Reputation: Stick to veterinary-trusted manufacturers like Dechra, Ceva (Douxo), or VetPlus. These companies invest in clinical trials to prove their products actually kill fungus, whereas generic brands often don’t.

Active Ingredients: This is the most important factor. Look for Chlorhexidine or Miconazole for yeast/fungal infections. If your dog has crusty or scaly skin, ensure the formula also includes Salicylic Acid or Sulfur to strip away dead skin cells so the medication can work.

pH Balance: Never use human shampoo (pH 5.5) on a dog. Dogs have a neutral skin pH (~7.0-7.5). Using acidic human products will destroy their skin barrier and worsen the infection.

Contact Time: Medicated shampoos are treatments, not soaps. You generally need to leave them on for 10 minutes before rinsing. If a product doesn’t specify a contact time, it’s likely just a cosmetic wash, not a cure.

Scent vs. Function: Be wary of shampoos that smell heavily of perfume. Strong fragrances often mask odours without killing the bacteria causing them, and they can irritate sensitive, infected skin. A “clinical” or mild smell is often a sign of a better product.


Final Verdict: Which Shampoo Should You Choose?

Treating a fungal infection is about more than just cleaning off dirt—it is a medical intervention for your dog’s skin.

  • For Active Infections (Yeast/Ringworm): Don’t hesitate. Choose Douxo S3 Pyo or VetPlus Coatex. These are the heavy hitters that contain the clinical ingredients needed to kill spores and stop the itch.+1
  • For Greasy or Crusty Scales: ICF Zincoseb is your specialist choice. It will strip away the waxy buildup that fungi hide under, allowing the medication to work.
  • For Maintenance & Prevention: If the infection is cleared and you just want to keep it away, Aqueos and Cooper & Gracie are excellent for keeping the skin microbiome healthy without using harsh chemicals.+1

One Final Rule: No matter which medicated bottle you buy, remember the 10-Minute Rule. If you rinse the shampoo off immediately, you are pouring the cure down the drain. Let it sit, soothe your dog, and watch the skin heal.


Frequently Asked Questions

Do antifungal shampoos really work for dogs?

Yes. Look for antifungal ingredients like chlorhexidine and miconazole. According to a randomised veterinary trial, the combination of Chlorhexidine and Miconazole is clinically proven to reduce yeast counts in dogs by over 88%.

For best results, leave the lather on your dog’s skin for 10 minutes before rinsing, allowing the medication to work.

What is the best shampoo for a dog with a yeast infection?

The most effective shampoos for yeast (Malassezia) contain Chlorhexidine and Miconazole (like Douxo S3 Pyo or Malaseb alternatives). If your dog also has greasy or crusty skin, look for a formula with Salicylic Acid or Sulfur (like VetPlus Coatex) to strip away the waxy buildup so the antifungal medicine can penetrate deeper.

Why does my dog smell like corn chips (or Fritos)?

This distinct smell is caused by a mix of natural bacteria (Pseudomonas) and yeast growing on your dog’s skin, particularly in the paws. While a mild smell is normal, a strong, musty “corn chip” odour usually indicates a yeast overgrowth. Bathing your dog with a Chlorhexidine or Miconazole shampoo (like Douxo S3 Pyo) will kill the yeast and eliminate the smell.

Can I use human antifungal shampoo (like Nizoral) on my dog?

No, you should not. Human skin is more acidic (pH 5.5), while dog skin is more neutral (pH 7.0-7.5). Using strong human dandruff or antifungal shampoos can destroy your dog’s protective skin barrier, leading to severe irritation and making the infection worse. Always use a veterinary-approved product.

How often should I bathe a dog with a fungal infection?

For active infections, vets typically recommend bathing 2 to 3 times per week for the first 2-3 weeks. This frequent bathing lowers the number of fungal spores on the skin. Once the skin heals and the smell goes away, you can reduce bathing to once a week or as needed for maintenance.

Is medicated shampoo safe for puppies?

Most medicated shampoos are safe for puppies over 12 weeks old, but you should always check the label. For young puppies under 3 months, their skin is more permeable and sensitive. If a young puppy has a skin infection, consult a vet before using strong chemicals like Chlorhexidine; they may recommend a gentler, natural alternative or a lower concentration.

What happens if my dog licks the medicated shampoo?

ou must stop your dog from licking the shampoo during the 10-minute contact time. Ingesting small amounts of Chlorhexidine or Miconazole can cause drooling, vomiting, or an upset stomach. If your dog swallows a large amount, contact your vet immediately. Pro tip: Feed your dog high-value treats (like peanut butter on a lick mat) during the bath to keep their mouth busy and away from the foam.

What kills ringworm in dogs instantly?

Nothing kills ringworm “instantly,” but a shampoo with Chlorhexidine and Miconazole is the fastest topical treatment. Ringworm is highly contagious, so you should use these medicated shampoos alongside oral medication prescribed by your vet to stop it from spreading to other pets or humans.

Is there an antiseptic, medicated shampoo for dogs?

Yes. Most veterinary shampoos are “dual-action,” meaning they are both antiseptic (killing bacteria) and antifungal (killing yeast).

For Infections: Products like Douxo S3 Pyo and VetPlus Coatex are strong medicated antiseptics designed to treat active skin conditions.

For Hygiene: If you just want to disinfect a dirty dog (e.g., after rolling in fox poo) without using harsh medication, use a gentler antibacterial shampoo like Aqueos.

Safety Note: Do not use strong medicated shampoos on healthy dogs as a “preventative,” as they can strip natural oils and dry out the coat.


About the author
Syed
Syed is a canine safety researcher and the founder of FlexK9. After raising Dexter, his 40kg Cane Corso, Syed became frustrated with the lack of reliable safety information for strong breeds. He now applies his background in data analysis to rigorously vetting dog gear, nutrition, and training tools. If a product can't pass the 'Dexter Test' or stand up to our deep-dive research, it doesn't make the list.